First,time and cost associated with producing plates and printing press setup. 

Every printing technology has its own identifying marks, as does offset printing. In text reproduction, the type edges are sharp and have clear outlines. The paper surrounding the ink dots is usually unprinted. The halftone dots are always hexagonal though there are different screening methods.

Second,propensity for anodized aluminum printing plates to become sensitive (due to chemical oxidation) and print in non-image–background areas when developed plates are not cared for properly;

Third,slightly inferior image quality compared to rotogravure or photogravure printing;